Rejection hurts. According to a Reuters article, that "kicked-in-the-gut" feeling that you get when you're ignored at a party or not chosen for a team generates physical symptoms. According to the article, "Brain-imaging studies show that a social snub affects the brain precisely the way visceral pain does."

"When someone hurts your feelings, it really hurts you," states Matt Lieberman, a social psychologist at the University of California, Los Angeles, who worked on the study.

In the study, 13 "volunteers were given a task they did not know related to an experiment in social snubbing. Writing in the journal Science, Lieberman and Naomi Eisenberger said the brains of the volunteers lit up when they were rejected in virtually the same way as a person experiencing physical pain.

"In the English language we use physical metaphors to describe social pain like 'broken heart' and 'hurt feelings,"' said Eisenberger. "Now we see that there is good reason for this."